My 2010 C300 had the left front TPMS sensor not working for months. The occasional web search turns up so much information that is actually irrelevant to this job. This car requires no programming. This is a full "remove and replace" operation. I did everything at home using a electric jack and an old Nissan truck. The scissor jack had a hole in the top of the foot, I temporarily screwed a class 8 hex bolt to the top of the foot to act as a centering pin. I used my truck's weight over the tire with the jack centered in a random hole in the truck frame. Featuring a flat tire and some manual adjustments to line up the bottom of the jack with the tire/wheel. I managed to break the bead and easily remove the TPMS sensor. The tire has a short 40 sidewall and I wasn't sure if this technique would work, but it turned out to be easier than expected. Getting this job done mostly involved figuring out the wheel/tire/jack and manually aligning it. After installing the TPMS, I inflated the tire to 35psi and then adjusted the pressure in all of the other tires to match the maximum pressure listed on the fuel filler flap. I reinstalled the front wheel, tightened all the eyebolts, and then pulled onto the freeway and off the ramp (about 2 miles). The TPMS warning light kept flashing and wouldn't go off until I slowed at the exit of the ramp. The lights were off at the traffic lights and all the pressure readings were on the dashboard. Here it is. nothing more was needed. I plan to replace the sensors when they fail. At around $45 for 4 it's a steal. Others have pointed out poor battery life, so time will tell if this really is a bargain.
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