This is my second Osprey Questa women's backpack and I only replaced the first one (bought in 2016) after something smelly spilled on it and I couldn't get rid of the smell. easily holds my 15.6 inch laptop as well as many other items including my portal scanner. It might fit a larger laptop, but you most likely won't be able to fit it in a laptop bag and you'll have to use the regular front panel, which is pretty roomy. It is comfortable to wear and fits my small stature well. (I'm 5'1"). I've used my old backpack several times in combination with a small carry-on for business trips. The Osprey backpack fits easily under the seat in front of me. (If there wasn't enough room to hear, I'd take my Put carry-on bags under the seat and my backpack (which is a bit smaller) on the ceiling. Great backpack for traveling. My only concern is that my original order got lost somewhere ( was quickly replaced) and the color I chose. My old one was blue but this time I ordered salmon pink it just looks all orange to me no pink tinge I was expecting it a bit lighter I guess but the color doesn't affect my use.
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