I have not experienced any issues with bristles falling out as some others may have, but I make a specific effort to allow my brush to dry out after each use and my bathroom is not very humid. Wood expands when it is constantly damp which I could see causing some bristles to fall out. They come in a pack of 4 though so if one falls apart just recycle it then open the next one. You are still better off than you would be using a plastic toothbrush.
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