I seem to have a combination of De Quervain's tendonitis and mild carpal tunnel syndrome (repeated sprain injuries from heavy keyboard and mouse use). When I first put this brace on I was amazed at how much pain relief it offered compared to my other wrist braces (I have five of them!). I also have very small wrists (5 3/4 inches in circumference) and a generally small frame, and the small size of this brace fits me very well. These braces appear to be well constructed and I think they will hold up well to everyday wear. It can also be hand washed. The thumb base is very good for what it is intended for. The disadvantage of this is that you are limited when wearing it. However, the other four fingers still have excellent posability. So if you need to stabilize your thumb this makes a great brace. If you don't need to constrain your thumb an open thumb brace may be appropriate.
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