The size of these bottles is large because there are so many toilet liquids that I don't really need a full 2 ounces for every trip. Unfortunately, they are not perfectly sealed. If the bottles are squeezed or pressure is applied to them, they will slowly leak. I noticed it immediately, but I still tested it on a short trip. Two bottles didn't flow, but one started to flow. They're likely to handle thicker or more gel-like liquids, and thinner or oily products are more prone to leaking. Another disadvantage is that some of the thicker products are difficult to inject into syringes and vials. The syringes worked great with thinner liquids, but cleaning and drying between each product was a fair amount of work.
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