I have a 46" chest and 36" waist and ordered them in size XL. The waist is more than enough but the chest is a little tighter than I would like for sleeping. However, it is a very comfortable garment and works well when the nights are cool but not cold - it is thin cotton. and no flannel. The pants have a (very long) drawstring to keep them tight. I recommend tying it with a bow tie or other simple knot before washing so one end doesn't get lost in the elastic at the waist. The shirt has three buttons and you must button at least one unless you are trying to be a disco superstar. The pants have spacious pockets and the pocket on the shirt is real but very small. As a bedtime garment before winter or just for lounging, this works really well.
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