Very easy to use for both developers & end users. Datomic has been very helpful in building my first real database solution. I have had issues with replication but this seems like something they are working towards solving (since version 0.9). Also not sure if there was some performance hit when using Redis or Memcached instead of MongoDB itself - however we were able to switch our application over fairly quickly after getting those things sorted out. We're still trying to figure out how best utilize its capabilities. Have built most components ourselves from scratch though their open source offering has helped us get started faster than expected!