I feel like something is missing when I leave the house in the morning without a handkerchief, with or without a cold. I keep something in my pocket to wipe my sweaty forehead, wipe my glasses, cover up an accidental sneeze, or temporarily bandage a cut finger. I personally find that a properly washed and carefully folded handkerchief is perhaps more hygienic than a tiny handkerchief, which invariably leaves more "residue" on my hands than a handkerchief. Is it important to wash your hands properly and frequently? It's been over ten years since I bought a pack of tissues so I was very happy when they arrived. I now have a refilled stack to wash as needed and starch and iron from time to time. This is a quality product that works as intended!