I've been using mice since 1985 so my hand took a lot of retraining but it was worth the effort. I'm a left-hander who broke my left wrist once, so it's not quite right; After a few hours of work, my hand became numb and my wrist hurt. I just got this mouse yesterday afternoon, played games with it in the afternoons to get used to the mirrored button layout, and then worked for a few hours in the afternoons (I do 3D modelling). And by the end of the evening I had no pain or numbness. After 30+ years of using right-handed mice, the button layout still confuses me, but I appreciate that the LMB is now under my index finger. , and additional buttons are easily reachable with your thumb. The entire mouse fits my hand perfectly, and with the racing stripes and dorsal fin profile, it's an absolutely insane device. - nervous in every direction, unreliable. I use the Blender software 3 to 6 hours a day, which depends on the scroll wheel being the middle button, so the wheel used was heavier than usual. Also, my arm tends to return to a vertical position while working, which means I'm putting unnatural pressure on the steering wheel at the wrong angle. The mouse endured this punishment for about 6 weeks. Maybe the company could take care of that as I'm probably not the only customer with ingrained usage habits. Aside from that, my arm and hand feel much, much better since using this mouse.
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