I love these shoes. I run 10-30 miles a week and have been wearing them for a year. I typically run 6-12 miles straight and they hold up great. I love them so much I own five pairs and I'm upset that they switched to the new model so quickly. I've also been using the Kinvara 4 for almost a year and although this shoe is lighter, I've had far more problems with blisters on the tips of my toes (and it's not because they were too small - I have a much longer second toe, so the purchase larger size will aggravate callus problems throughout the foot). The Kinvara 5 has a roomy toe box and plenty of width for medium to long-distance runners.
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