I recently had a ligament problem and had to have my wrist spliced. and I had to have a bone removed from my thumb due to arthritis issues. The only issue I've had so far is that the enter key is missing every now and then, but overall I'm quite happy. Using a mouse is still difficult for me, and adapting to this style of mouse is the only option I think is suitable. I use roller mice and wireless mice, but since I can't bend my wrist, I needed one. I can't tell you anything about longevity. I have a mouse that has been with me for 20 years, so I will not rate it at that level.
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