
Actually I bought medium and large bags because I wasn't sure which size to choose and I can say with confidence that you want a large one, even if you don't I don't have much to wear. And therefore! First, the build quality. The big one has a lot more weight and padding on the top valve, the middle one doesn't. Overall, the large size feels much softer and has better padding than the medium size. Also, the large backpack has two buckles on the front and not one on the middle one. Together you feel much more reliable! Second bags. The middle one has an extra pocket on the front and is SMALL. I could put in a few batteries and a filter or two, but nothing more. The large one has pockets on both sides as well as a larger front pocket and another pocket that acts as an inner zip cover under the flap. More pockets for wallet, phone, batteries, lens hood, etc. Third size. The medium one is only slightly smaller than the large one, but carries far fewer things. I could hardly fit my camera with a regular lens and flash, that's all. However, they fit in the large, as well as an additional 200mm and 28mm lens with the lens hood attached and even more space for other things! So, for just a few dollars more, you get a lot more out of a large bag than a medium-sized one. Trust me, just take the big one. PS I solved the "squeaky seat belt clips" problem by quickly spraying the connections with silicone spray. Safe to use on plastic and the squeaks are gone!

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