I first tried Puffs Plus with lotion when they first came out. Back then, lotion was different and seemed to leave slippery marks on hands after use. These days the wipes feel a lot drier and leave no residue, but they still offer the same protection for my nose. red, raw and scaly. My nose loves these lotion soaked wipes. But even if I don't have a cold, these wipes are still preferable. You see, regular fabrics, even puffs, get soaked. Lotion wipes resist this, perhaps because they are already soaked in lotion. This means my fingers aren't wet and contaminated with germs after blowing my nose. They're also better for storing liquids of all kinds, although not as good at soaking up spills.
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