The real problem is that space is wasted when opening. Many pockets have 1 zipper, so it's difficult to open them and get what you want. It has a flap/double zip design so the entire top opens up. That makes the usable space huge. It's also great to have 2 completely "open" sides. And the "leather" (?) material seems pretty durable. Although the bag is quite big. That's exactly what I want for me as I bring so much with me; not just toiletries, but a huge range of medication and items I might need in an emergency, from TheraFlu to a lint roller. One photo shows the whole space, another photo shows how big it is in a 21 inch carry-on.
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