Although the interface is very confusing, I can confirm that this tool can remove or add 2011 Lexus IS250 entry and start Smart Key. The 2011 IS comes with a smart key, not a regular "fob" (where the remote and immobilized chip are separate). Therefore, the key fob or the remote menu on the instrument will not work. Only the smart key menu works. To delete a key, you must physically own the key and have at least two or more keys registered in the system. Go to the automatic menu, select the delete button and follow the instructions. You can't remove the last key, you can't remove the key in someone else's pocket. This device cannot add a key. To add a key, you must have all current and new keys to hand. Go to the manual method, select "Clear Smart Boxโ and then wait 16 minutes with the engine running and the door left open. After deleting the smart box, add a key, go back to add a key and then add another. If you don't reset the smart box, the tool can't add the key. A buttonless smart key is around $150 at some dealers, this tool will save you on a Lexus trip and around $300 on a program.
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