I bought this specifically for a trip to Europe where it will be my only backpack and also a wheeled bag. It's a 350. I fit in: a Canon 70D with a bulky kit lens, 18-135, with a strap wrapped around the lens; wide angle 10-18; Tele 15-250; 1 Canon 430 Speedlite flash; and a cloth bag with cleaning supplies. All of this fits into the camera compartment, which opens "at the back" - you either have to remove the packaging or "turn it over": there is no other access. A full frame DSLR can get very cramped, but the bag fits my crop camera. And restricted access is a plus for security. I really like the spacious separate upper pockets. In the main bag I pack my filter system, a small suitcase with batteries and other photo accessories and a few small bags with personal items. The small front pocket holds an iPad, a large glasses case and a small notepad. Probably no room for a laptop! Please note that there are no other external pockets apart from one on the hip belt. However, I have a feeling that people will find it more difficult to open their pockets when lying on their backs. (I have zippered safety clips for when I'm in a crowd). I've only used the flip function a few times to change lenses in the field and it worked well. If you were wearing a thick jacket, it wouldn't be that easy. I like the size, the ability to adjust the straps when dressing; Side and back straps for water bottle, tripod, walking stick or whatever. It is convenient and easy to adjust the harness and shoulder straps for weight distribution. I'm picky, but this one has served me well after two months of use.
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