So I've tried frowns, derma and facial smoothies (I tend to exaggerate the issue) and they all have their pros and cons, but toute nuit is now my favorite. I find these patches are most effective when the wrinkles are relatively new. Now that I'm in my 30's I have this laugh line on one side of my face. Sleeping on your side doesn't help. Home peeling used to treat, but not now. Just one night with them and it's gone! Of course I will continue to use every night and then cut back to a few times a week but I'm impressed.
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