5-HTP has been used worldwide for many years. However, I found that taking very high doses (my stupidity) caused a blood clot to form in a blood vessel in one eye, resulting in a 50% loss of vision. It appears that when taken in high doses, 5-HTP can cause serotonin syndrome, in which serotonin is now released into the bloodstream instead of to its intended target, the brain. I stopped taking it, took a baby aspirin and my vision went back to normal. I found that 5-HTP also increased my cortisol levels, which made me feel jittery and slept less. Instead I will try L-Tryptophan in combination. with GABA for sleep.
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