I wear size 14 6E shoes and use custom orthotics. The 1540 features an SL-2 last that fits my foot better than any other shoe. They have been out of stock for a few years and I was lucky enough to get the only pair in stock a few weeks ago. Although these are running shoes, I mainly use them for walking and commuting. Ortho shoes have more cushioning and are lighter on my 72 year old knees, but they are more stable and fit much better.