I highly recommend following directions and taking them on an empty stomach in the morning. When I got my first bottle I was so eager to try it that I drank it after dinner and threw up. I almost gave it up, but something told me to keep taking it. I did this in the morning before meals and WOW. It may take a while, but he does what he says. If you meditate and are in tune with your body, you will feel it very soon, maybe even on the first day. If not, please be patient. If you have been meditating for some time (months or years) before taking it, I think it would be really good. I feel it most when I meditate and dream. I also had toothaches only at night for several months, which went away after a few days.
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