My 10 month old healthy puppy had an allergic reaction to something in this collar. Her eyes were red, swollen, and moist from wearing them overnight, and she was visibly uncomfortable. Immediately removed the collar, washed all the bedding and taken to the vet. After using an antibiotic ointment, it took about 4 days for the infection in her eyes to clear up. Her eyes STILL get wet each morning after not wearing them for a month, but the redness and irritation seem to have gone. I am not sure if she will ever fully recover. This collar not only had NO calming effect but also caused her and my wallet discomfort which made this purchase a terrible one for us. It was recommended by a friend who says it works great with her dog so it's a gamble.
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