My Prius has had intermittent misfires for a long time (89,000 miles now). Maybe one of the original spark plugs died. After unscrewing more parts than I expected, I was able to replace the original 2006 plugs with these. Now it runs smooth as silk! My mileage has increased by at least 3mpg - from 42mpg to 45mpg. I have low profile tires and drive like a maniac so 45mpg is pretty good. I used a similar Platinum +4 in my 1995 Integra. It also ran smoother after that, but didn't get a lot of mpg.
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