I've been using this detergent on all my dress pants and shirts for years. I've never done clinical studies, but I'm convinced that Woolite Darks detergent has less of an impact on clothes than regular detergent (like Tide). For example, my khaki pants still look new after many years of washing. Although it is sensitive to clothes, it still cleans my clothes perfectly. I recommend washing on the gentle cycle with cold water only. I have a front loading HE machine and it works great with this detergent.
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