I was able to deflate the tires on my 2015 GMC Denali 2500 but it wasn't easy. Make sure you use a brand new 9v battery as anything a bit old will not work properly. It took a few times to get all four wheels working properly, so be patient. I followed all the instructions that way, but I had to move the device to a slightly different spot on the bus and press (and in some cases hold) the button for the car to get a signal. With some tires it worked the first time, with others I had to press up to 10 times before it worked. Although I was able to restart the machine, it wasn't easy and didn't always work out well.