I have been using Nioxin 3 for a long time but based on the description I decided to order Nioxin 5 shampoo and conditioner this time. (I have permed white/grey hair, not colored.) I like it a lot; there doesn't seem to be much of a difference between 5 and 3, but since the quarantine has been going on for 2.5 months, it's time for my next perm. (I'll come back to edit this review if the perm makes a big difference.) Overall I think my hair is hydrated with both Nioxin numbers without feeling heavy. And while it doesn't cure my itchy scalp (just itching, no dandruff), it does the job better than other shampoos I've tried. I don't usually buy expensive cosmetics, but I think they're worth it.
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