I really like this wrist compression sleeve. I have Ehlers-Danlos Hypermobility Syndrome and I have to wake up at night. This sleeve is comfortable and flexible. It supports my thumb well without twisting it. There is a large seam connecting the index finger to the thumb area. It runs along the fabric of your hand. It doesn't bother me at all and I'm rather sensitive. However, I ordered XXL. My height is 5 feet 8 inches. I have pretty big hands. I will definitely be buying more when this wears out and for another hand!
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