After 3 weeks of heavy business travel through remote villages, factories, city streets and various side adventures, I've become a big fan of Timbuk2. It was comfortable despite being loaded with heavy electronics, travel essentials, etc., even during a sprint or two between airport gates. Covered zippers keep dust out, while mesh vents keep it cool on the hottest days. Internal organization makes it easy to find everything and, more importantly, painless unload/reload at checkpoints. The water bottle's side sleeve stretches enough to accommodate multiple odd-shaped bottles, but holds them tight enough to withstand a toss. My Maui Jim fits in the top goggle pocket in its 2.5 inch wide case. A built-in lanyard keeps my keys safe and secure until I get home after walking around the wet parking lot with my hands full and needing to find them quickly. While I haven't tested it for water resistance yet, I gave the outside a good wipe with a soapy cloth and the inside seemed to stay completely dry. I was hesitant to buy this because of the price but would do it again no questions asked. and have already recommended the brand to several people.
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