This sublingual tablet tasted weird at first, but after the first try I got used to it. This is an incredible, almost instantaneous mood booster. Be careful not to take this within 2 hours of supplementing with B6 for ideal use. (but add B6!). This is because B6 binds to 5-htp in the liver and is then unable to cross the brain barrier. This is also why sublingual tablets are by far the best way to take 5-htp, as opposed to sip tablets which go through the stomach and intestines. When administered sublingually, unlike tablets, which can irritate the stomach and intestines, 5-htp enters the bloodstream directly and is then partially filtered out by the liver through a "first pass" before entering the bloodstream, reducing potency. But even when taken sublingually, it circulates and ends up in the liver, albeit to a lesser extent, so it's still important not to take B-6 within two hours of taking the supplement as directed. I am amazed at the effects of this. additive. When I'm feeling down and it's not related to sleep, food, or other mitigating circumstances, I know it's a brain chemistry issue and this pill seems to help balance that issue.
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