I drank 1 shot followed by a headache and for me it is sometimes caused by sucralose. If you read more, sucralose seems completely incompatible with intermittent fasting. I try a 5:2 plan and on my fasting days I eat less than 600 calories at 1am and then fast for 24 hours. It takes 24 hours for autophagy (cell regeneration) to start/occur. Some people eat 3 small meals under 500/600 calories, but autophagy only kicks in after 16 hours without water, so that doesn't work for me. In any case, IF helps deal with insulin and sugar, and sucralose completely messes it up, even more so than real sugar. I usually drink pre-workout on the non-fasting day, but artificial sweeteners are out of the question for me.
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