No problem, no programming required. I have a 2006 Acura RL and one of the TPMS sensors is out of battery. As I've been told in several places, it's better to change them all because as soon as one goes, they all end. If someone stops working at RL, the whole system will stop working anyway. Japanese technique for you lol. Just kidding, I really love this car. Anyway, over $500 at various locations for parts, labor and programming. Then I found this, no programming required? What a dream! America's Tire installed them for $120 which included repositioning and balancing all 4 tires. After installation, the car didn't recognize them right away, drove about 3 miles and they read "strange", but a few miles later they were all correct. So they should work on Acura RL 2nd Gen 2005-2012 without additional programming. Enjoy!