I have arthritis in both hands. Haven't tried the water bottle yet but most other bottles I have such as V8 Juice, Soy Sauce, Teriyaki, BBQ Sauce to name a few. they do not fit. I already had a bottle opener but this works too, I like opening the pull tab on a can because it's easier to hold than say a knife but that's a lot of money for so few uses. I wish that was the full answer.
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