These pills calm my Great Dane puppy very well. He weighs about 130 pounds and I give him three pills. The pills must be delicious because he just eats them like that. Three pills calms him down and makes him less bothersome when I go to work. The bottle says I can give him more, but three will help. This product has also worked well on my previous dogs. It doesn't make the dog sleepy (at least not at the dose I'm giving him) but rather calms him down. The tablets work quickly. I'm not sure how long they will last.
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