Both are isothiazolinones, known skin sensitizers. Methylisothiazolinone was named Allergen of the Year for 2013 by the American Contact Dermatitis Society, and benzisothiazolinone (BIT) has a similar structure. They are associated with allergic contact dermatitis (ACD), and since ACD may have a delayed response, patients may not see the connection; Some may wonder why their skin itches, flakes, turns red, or does something else. Airborne contact dermatitis has even been reported in individuals exposed to water-based paints containing isothiazolinones. Isothiazolinones (chills/gagging) have been used in baby wipes, makeup removers, shampoos, sunscreens, cleansers and paints. So read the labels and learn more about your skin risks! The EU started restricting isothiazolinones a few years ago following a spike in eczema cases, but I doubt anyone has fully deciphered the potential skin damage or what else might be involved. However, manufacturers only try to protect products from the growth of bacteria or mold.
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