They are great for drilling small holes in drywall. . . but if you try that, I recommend using a hammer instead. The holes get bigger and you make them faster. Really, even for random, useless holes, these anchors are not suitable. The problem is that these anchors don't "pop open" behind the drywall. There is nothing that could hook the anchor to the drywall. So after putting the plastic anchor into the wall when I tried to insert the screw I couldn't get it all the way in because the anchor just started rotating in the drywall even after a few turns. Strange. Just buy something that will stick better to the drywall, there are plenty of other options. That's stupid.
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