Seachem is the absolute finest line of aquarium care products. Safe is a powder form of Seachem Prime and is a much cheaper alternative. It is very easy to use and requires very little due to its concentrated formula. I've been using it on 13 tanks for more than 5 years. I even use it to quickly switch aquariums to add fish right away (not the best way to introduce fish, but sometimes necessary). The safe stores your chlorine during checkout hours. It is used as a water conditioner during water changes, but can also be used as an ammonia control additive. The Seachem website has all the answers you need. If you have multiple tanks or just want to save some money, choose Safe.
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