I used these to attach a sink pedestal to my bathroom wall. You will need to drill a 1/2 inch hole for the anchor, but this is slightly smaller than the old "molly" style anchors. Since I was drilling a brand new tile I wanted to drill as small a hole as possible and that was it. I had to get longer screws because I had to go through the sink, tile, cement board, and rail, but they were just standard 1/4"-20 screws, so it was easy. One of the 10 anchors was missing a plastic ring. That holds the anchor in place while you insert the bolt, so it's a bummer because without it it's probably useless.
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