Apply after cleansing. Then use a moisturizer. It instantly brightens the complexion and leaves skin incredibly hydrated. I have dry skin in addition to using retinoids that cause flaky skin and I have no problem using glycolic acid twice a day. In fact, this is a great way to smooth skin that is constantly flaky. And as other people have mentioned, my makeup is much easier to apply, it glides over my skin when there is toner underneath. If your skin is very sensitive or you really don't like the tingling, you might not like it. But in my opinion, the sensation is nothing. It doesn't hurt very much and then goes away as soon as you put cream on it. Sometimes I get short red spots in certain areas which I think will come after leaving it for an extra minute, but that goes away quickly. I love this product and I highly recommend it!
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