I could not find any negative effects such as cloudiness or a negative reaction from my cichlid. Use as directed and if you are not sure if you need the full dose, start with half the dose and give the aquarium 3-6 hours to mix and shake as the PH will not change in any solution, including aquariums, immediately adapts. I use this in conjunction with their mineral supplement to harden the water to maintain mineral rich water in my tank along with a high (e)PH for my cichlid and although I don't clean my tank as often as necessary and for long periods of time do between waterings. Quality and setup tests, alkalinity and mineral levels do not vary, or vary very little, unless I top up my aquarium with water without re-adding the appropriate amount of alkaline buffer and minerals.
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