I have given this to my 60lbs dog three times now (two chewables). After about 40 minutes, she appears to be more relaxed/tired. I feel like it lasts for roughly 3 hours or so. She gets anxiety if during the week, I leave the house for an extended period of time. I wanted to see the effects of this while I was home before ever leaving her alone. From time to time, she might mess by the door due to her anxiety, so this will be the ultimate test. Overall, it appears to work.
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