Review on Instant Ocean BIO-Spira 100mL: Safeguard Your Marine Aquarium with Ease by April Bailey

These live bacteria work very well to quickly create a colony that can handle ammonia right away. I use it in my seawater quarantine/hospital tanks that don't have the luxury of waiting a week for a cycle. I still monitor my ammonia levels with an alert icon and dose Seachem Prime as needed, but I have found that Bio-Spira works reliably as an effective biological filter. It takes time for the bacteria that convert nitrites to nitrates to develop, but that's not a big deal in salt water, especially in a fish situation.