I've used this with about 10 canisters of refrigerant so far without any problems. Before using it I loosened and re-tightened the Schrader valves on the R12 and R134a fittings and had no problem holding pressure at the tap. I left the bottle on the faucet connected to the pressure gauges for over a week and at the end of the week I didn't notice a drop in pressure.
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